Stem cell therapy is a new and emerging field that enhances our traditional treatment of previously difficult to manage conditions, including osteoarthritis and tendon injury.
Stem cells are divided into two types, embryonic and adult stem cells. Of the adult stem cells there are haematopoietic stem cells that can build blood and blood products, mesenchymal stem cells that can build muscle, bone, ligaments, tendons, cartilage and fat and neural stem cells that build nerve tissues. The stem cells that we use are mesenchymal stem cells derived from fat. The tissue is harvested from a donor at the time of routine desexing procedures. The stem cells are cultured and prepared and stored in liquid nitrogen prior to use. Stem cells are carefully thawed to room temperature before being transplanted into the patient.
Stem cells work in two different ways:
1. They can act to regenerate damaged or lost tissue.
- by changing into new cell types, such as cartilage or bone
- they can secrete molecules to tell other cells in the joint how to act to repair tissue within the joint
2. The can downregulate the inflammatory cascade.
- Ischaemic damage (low oxygen supply) - renal failure, stroke or heart attack
- Overactive immune responses - rheumatoid arthritis, multiple sclerosis
- Overactive inflammatory responses - osteoarthritis
Stem cells are injected into the affected area (joint or tendon) using a sterile technique. The transplanted cells embed in the lining of the joint or tendon and secrete molecules into active neighbouring or target cells. These cells in turn
- Improve blood flow
- Recruit other cells for repair of injury
- Prevent cell death
- Stimulate regeneration
- Improve function of cells
- Anti-inflammatory effects
AREC and New Life Vets are exited about the opportunities stem cell therapies provide to help old patients, suffering from arthritis. Our vision is to bring 'new life' to old or injured dogs.
One in five dogs suffers from osteoarthritis. Osteoarthritis is caused by the mechanical wear and tear of joints and can result from injury (cruciate rupture, some fractures), developmental problems (OCD) and conformational problems (elbow and hip displasia, luxating patellas).
Because stem cell therapies are still being developed, and because the treatment is not yet registered with the AVPMA (veterinary drug regulatory body) stem cells can be provided for your pet under permit no. 7250. This means that clients are enrolled in a study conducted by our supplier, Regeneus. Data is collected from your client's pet, recording the pet's response, pain levels efficacy and safety.
REFERRALS ARE BY APPOINTMENT ONLY - PHONE 02 4957 7106
Veterinarians can complete our on-line referral form